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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MAP2K6 All Species: 14.55
Human Site: T322 Identified Species: 26.67
UniProt: P52564 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P52564 NP_002749.2 334 37492 T322 T L H E S K G T D V A S F V K
Chimpanzee Pan troglodytes Q9XT09 393 43428 V369 K R S D A E E V D F A G W L C
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_851023 334 37590 T322 T L H E S K A T D V A S F V K
Cat Felis silvestris
Mouse Mus musculus P70236 334 37414 A322 T V H E S K A A D V A S F V K
Rat Rattus norvegicus Q4KSH7 419 47517 E387 I K H Y E T L E V D V A S W F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511595 352 40240 T338 N L H K T K E T D I A A F V I
Chicken Gallus gallus Q90891 398 44059 V375 K R S E V E E V D F A G W L C
Frog Xenopus laevis Q07192 446 50082 E419 P F I L M Y E E R T V D V A G
Zebra Danio Brachydanio rerio Q9DGE0 361 40575 T349 T L H D S K D T D V A S F V K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_477162 334 38176 T315 V E H L Q R N T D I S E F V A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q20347 363 41178 G337 Y R I Y A V A G P E I E E A K
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9S7U9 363 39830 I338 N K Y D Y S G I N L A S Y F T
Baker's Yeast Sacchar. cerevisiae P08018 668 72701 V631 V K Y R N Q D V H M S E Y I T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 32 N.A. 98.8 N.A. 97.9 38.6 N.A. 75.2 34.4 43.5 80.6 N.A. 58.6 N.A. 38.2 N.A.
Protein Similarity: 100 47.8 N.A. 99 N.A. 99 53.7 N.A. 85.5 51.5 56 85.8 N.A. 74.8 N.A. 56.2 N.A.
P-Site Identity: 100 13.3 N.A. 93.3 N.A. 80 6.6 N.A. 53.3 20 0 86.6 N.A. 33.3 N.A. 6.6 N.A.
P-Site Similarity: 100 46.6 N.A. 93.3 N.A. 86.6 13.3 N.A. 80 40 0 93.3 N.A. 53.3 N.A. 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 31.9 24.2 N.A.
Protein Similarity: N.A. N.A. N.A. 53.1 36 N.A.
P-Site Identity: N.A. N.A. N.A. 20 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 53.3 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 16 0 24 8 0 0 62 16 0 16 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 16 % C
% Asp: 0 0 0 24 0 0 16 0 62 8 0 8 0 0 0 % D
% Glu: 0 8 0 31 8 16 31 16 0 8 0 24 8 0 0 % E
% Phe: 0 8 0 0 0 0 0 0 0 16 0 0 47 8 8 % F
% Gly: 0 0 0 0 0 0 16 8 0 0 0 16 0 0 8 % G
% His: 0 0 54 0 0 0 0 0 8 0 0 0 0 0 0 % H
% Ile: 8 0 16 0 0 0 0 8 0 16 8 0 0 8 8 % I
% Lys: 16 24 0 8 0 39 0 0 0 0 0 0 0 0 39 % K
% Leu: 0 31 0 16 0 0 8 0 0 8 0 0 0 16 0 % L
% Met: 0 0 0 0 8 0 0 0 0 8 0 0 0 0 0 % M
% Asn: 16 0 0 0 8 0 8 0 8 0 0 0 0 0 0 % N
% Pro: 8 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 8 8 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 24 0 8 0 8 0 0 8 0 0 0 0 0 0 % R
% Ser: 0 0 16 0 31 8 0 0 0 0 16 39 8 0 0 % S
% Thr: 31 0 0 0 8 8 0 39 0 8 0 0 0 0 16 % T
% Val: 16 8 0 0 8 8 0 24 8 31 16 0 8 47 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 16 8 0 % W
% Tyr: 8 0 16 16 8 8 0 0 0 0 0 0 16 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _